FETAL HYDANTOIN SYNDROME PDF

Disease definition. Fetal hydantoin syndrome is a drug-related embryofetopathy that can occur when an embryo/fetus is exposed to the anticonvulsant drug. A clinical diagnosis of fetal hydantoin syndrome secondary to in utero phenytoin exposure was considered. Investigations showed vitamin D. This page includes the following topics and synonyms: Fetal Hydantoin Syndrome.

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Together we are strong. Researchers believe that the protein product of this gene plays a role in the proper breakdown metabolism of phenytoin or one of its metabolites. The range and severity of associated abnormalities may vary greatly from one infant to another. Various methods of rehabilitative and behavioral therapy may be beneficial. Infants with fetal valproate syndrome are at a greater risk of developing neurological abnormalities than are infants whose mothers took other types of anti-seizure medications.

Definition Congenital syndrome due to in-utero Phenytoin exposure. Summary and related texts. Additional information Further information on this disease Classification s 6 Gene s 0 Clinical signs and symptoms Publications in PubMed Other website s 3. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy.

Fetal hydantoin syndrome

Postoperative view of maxillary arch Click here to view. Although some disorders due to specific drugs e. Some infants may have increased hair on the body and face.

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Retrieved from ” https: Some infants and children may hydantoib delays in reaching developmental milestones such as learning to sit up or crawl developmental delays. Cleft palate may be repaired by surgery or covered hydatoin an artificial device prosthesis that closes or blocks the opening. NORD has a separate report called fetal valproate syndrome that discusses infants whose mothers took valproate during pregnancy.

Inguinal hernia is when a portion of the intestines pushes through the muscular layers of the abdominal wall. Languages Polski Edit links.

Views Read Edit View history. Borderline to mild intellectual disability has been reported in some cases, and some studies have suggested that children exposed to phenytoin in the womb have a greater risk of developing learning disabilities, particularly in verbal skills. It is important to note that the majority of infants born to women who take phenytoin during pregnancy will not develop fetal hydantoin syndrome.

World Health Organization; Elsevier Saunders, Philadelphia, PA; Affected Populations Fetal hydantoin syndrome affects males and females in equal numbers. Fetal hydantoin syndrome C Obstetrics – Pharmacology Pages. Although access to this website is not restricted, the information found here is intended for use by medical providers.

Related links to external sites from Bing. Distinctive facial features may be present including a flat, broad bridge of the nose; a short nose; eyes that are farther apart from each other than usual hypertelorism ; crossed eyes strabismus ; eyelids that droop ptosis ; a large, wide mouth; malformed ears; mild webbing of the neck pterygium colli ; and microcephaly.

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The epidemiology of epilepsy in Rochester, Minnesota, through Infobox medical condition new Articles to be expanded from March All articles to be expanded Articles with empty sections from March All articles with empty sections Articles using getal message boxes. Back Links pages that link to this page.

Fetal hydantoin syndrome – Wikipedia

Lateral profi le Click here to view. Anti-seizure medications, also known as antiepileptic or anticonvulsant medications are among the most common teratogens prescribed to women of childbearing age. Search Bing for all related images. Cleft lip may be surgically corrected. Sridharan R, Murthy BN.

Fetal Hydantoin Syndrome

Limping walk Click here to view. Surgical repair can be carried out in stages or in a single operation, according to the nature and severity of the defect. Related Bing Images Extra: Related articles Anticonvulsants crossbite phenytoin space maintainer. Comparisons may be useful for a differential diagnosis. Another theory speculates that ayndrome metabolites of phenytoin are responsible for its teratogenesis.

Investigational Therapies Information on current clinical trials is posted on the Internet at www.