Elastosis perforans serpiginosa (EPS) is a rare disorder classified as a primary perforating dermatosis. That group of diseases also includes. Four types of elastosis perforans serpiginosa (EPS) have been described in literature: 1) idiopathic EPS, 2) reactive perforating elastosis. Elastosis perforans serpiginosa (EPS) is a rare dermatologic condition where connective and elastic tissues are viewed as foreign objects and subsequently.

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Tazarotene Is an Effective Therapy for Elastosis Perforans Serpiginosa

Purchase access Subscribe now. A case of elastosis perforans serpiginosa associated with pseudoxanthoma elasticum. Penicillamine-induced pseudoxanthoma elasticum with elastosis perforans serpiginosa: Elastosis perforans serpiginosa EPS is a peeforans skin disorder in which abnormal elastic tissue fibre passes from the papillary dermis inner layer of skin to the epidermis outer layer of skin.

Support Center Support Center. In cases of elastsis EPS, calcification can be observed between the collagen fibers [ 1 — 4 ].

Biopsy specimen demonstrating transepidermal elimination of altered elastic fibers. YAG, and dye lasers. The last subtype, idiopathic one, may be associated with genetic basis of the autosomal dominant type of inheritance. This condition elastoais inherited in an autosomal dominant manner.

Elastosis perforans serpiginosa on the background with acanthosis nigricans.

The channel opens into a bowl-shaped cavity filled with horny plug. Serpkginosa pinhole method using a carbon dioxide laser showed complete clearing without post-treatment scarring The lesions developed 1 sedpiginosa after a revised facial rhytidectomy scar revision.


Penicillamine-induced elastosis perforans serpiginosa and cutis laxa in a patient with Wilson’s disease. Journal List Postepy Dermatol Alergol v.

Verhoeff-van Gieson staining showed a markedly increased number of altered elastic fibers forming dense clumps in the upper dermis Fig.

Elastosis perforans serpiginosa – Wikipedia

Psoriasis and Down syndrome: The patient’s medical and family history was also negative for EPS or any other connective tissue diseases. The middle of each lesion is umbilicated from which the material containing damaged elastic fibers is extruded [ 12 ].

Abstract Elastosis perforans serpiginosa is a rare skin disease characterized by transepidermal elimination of abnormal elastic fibers. Create a free personal account to access your subscriptions, sign up for alerts, and more.

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Cutaneous lupus erythematosus chronic: Characteristic for EPS skin lesions within face A and left upper extremity B, C — papular keratotic lesions fuced together in serpiginous arrangement. Disorders of connective tissue.

Click on image for details. Elastosis perforans serpiginosa is considered as mild dermatosis, which is not accompanied by involvement of other organs [ 2 ].

To confirm the clinical diagnosis, the biopsy was taken from the primary circinate lesion of the cheek. In the first case, serpiginoaa they unsuccessfully used 3-month therapy with tretinoin cream, then cryotherapy was performed, yielding only a minimal improvement. There have not been published any reports about EPS and Koebner phenomenon so far. The patient had been treated with oral cephalexin for 2 weeks and topical erythromycin solution for several weeks, without improvement.


In the biopsies an increased amount of elastic fibers can be found, both just underneath the epidermis and in the reticular layer of the dermis. What is standard of care in the evaluation of elastosis perforans serpiginosa? Open in a separate window. All five Korean patients including our patient presented with skin lesions on the neck, the most frequently affected EPS site. Get free access to newly published articles.

Self-skin examination New smartphone apps to check your skin Learn more Sponsored content. From Wikipedia, the free encyclopedia. Localized scleroderma Localized morphea Morphea—lichen sclerosus et atrophicus overlap Generalized morphea Atrophoderma of Pasini and Pierini Pansclerotic morphea Morphea profunda Linear scleroderma.

Elastosis perforans serpiginosa: a review of the literature and our own experience

We report a case of D-penicillamine induced widespread alteration in skin elastic tissue with distinct histopathologic features. Long term D-penicillamine therapy causes an alteration in the dermal elastic tissue. We can distinguish three subtypes of EPS. Serpiginosx is an effective therapy for elastosis perforans serpiginosa.

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