Choriocarcinoma is a fast-growing cancer that occurs in a woman’s uterus (womb ). The abnormal cells start in the tissue that would normally. Hydatidiform mole (complete or partial); Invasive mole; Choriocarcinoma; Placental-site trophoblastic tumor; Epithelioid trophoblastic tumor. Find out about persistent trophoblastic disease (PTD) and choriocarcinoma.

Author: Voodoohn Shajora
Country: Mozambique
Language: English (Spanish)
Genre: Career
Published (Last): 8 April 2012
Pages: 308
PDF File Size: 17.30 Mb
ePub File Size: 19.55 Mb
ISBN: 793-3-88981-595-2
Downloads: 62588
Price: Free* [*Free Regsitration Required]
Uploader: Shazuru

Cytotrophoblasts are polyhedral, mononuclear cells with hyperchromatic nuclei and a clear or pale cytoplasm. A pregnancy test will be positive, even if you are not pregnant. Epithelioid trophoblastic tumor ETT is an extremely rare type of gestational trophoblastic disease that can be hard to diagnose.

Invasive moles develop in less than 1 out of 5 women who have had a complete mole removed. ETT used to be called atypical choriocarcinoma because the cells look like choriocarcinoma cells under the microscope, but it is now thought to be a separate disease. Choriocarcinomas can also occur in the ovaries. Call for an appointment with your health care provider if you develop symptoms within 1 year after a hydatidiform mole or pregnancy.

Micrograph of choriocarcinoma showing both of the components necessary for the diagnosis – cytotrophoblasts and syncytiotrophoblasts. Search our clinical trials database for all cancer trials and studies recruiting in the UK. Gestational trophoblastic disease GTD Persistent trophoblastic disease and choriocarcinoma.

Gestational trophoblastic disease treatment PDQ — health cgoriocarcinoma version. It is much more likely than other types of GTD to grow quickly and spread to organs away from the uterus. It uses a numbering system for both the stage and risk factor score.

Characteristic feature is the identification of intimately related syncytiotrophoblasts and cytotrophoblasts without formation of definite placental type villi. Gynaecological cancer Male genital neoplasia Germ cell neoplasia. Gestational trophoblastic disease GTD Persistent trophoblastic disease and choriocarcinoma.


Chorioczrcinoma refers to the word chorion, which is the outer covering membrane of the growing baby foetus. Choriocarcinoma is a malignant form of gestational trophoblastic disease GTD. Most women whose cancer has not spread can be cured and will still be able to have children. Extensive hemorrhage is a common finding. When you are diagnosed with persistent trophoblastic disease your choriodarcinoma look at certain risk factors that help them decide about chemotherapy treatment and which drugs are best for you.

About Cancer generously supported by Dangoor Education since They may develop in the ovaries, testicles, choriocacinoma, or abdomen. Choriocarcinoma is a malignant, trophoblastic [1] cancerusually of the placenta. Malignant diseases and pregnancy. Tumors and Pregnancy Read more. Choriocarcinoma only happens in about 1 in every 50, pregnancies and there are fewer than 20 cases a year in the UK. One prevalent symptom is vaginal bleeding after a pregnancy, abortion, or hydatid mole.

They choriodarcinoma spread to other parts of the body but are very likely to be cured by chemotherapy treatment. It also scores various risk factors to work out which treatment you need.

Acta Obstet Gynecol Scand. But these tumors have a tendency to grow into invade the muscle layer of the uterus. Choriocarcimoma trophoblastic tumor PSTT is a very rare form of GTDthat develops where the placenta attaches to the lining of the uterus. The same choriocarcnoma true of choriocarcinoma arising in the ovary.

Endometrioid tumor Uterine papillary serous carcinoma Endometrial intraepithelial neoplasia Uterine clear-cell carcinoma. Normal and Problem Pregnancies.

What Is Gestational Trophoblastic Disease?

Updated February 25, Choriocarcinoma Micrograph of choriocarcinoma showing both of the components necessary for the diagnosis – cytotrophoblasts and syncytiotrophoblasts. Find out about chemotherapy for low risk and high risk disease.


Gestational trophoblastic disease Hydatidiform mole Choriocarcinoma Placental site trophoblastic tumor Polyembryoma Gonadoblastoma. National Cancer Institute website.

Like placental-site trophoblastic tumors, ETT most often occurs after a full-term pregnancy, but it can take several years after the pregnancy for the ETT to occur. Persistent trophoblastic disease and choriocarcinomas are most commonly found in the womb but they can spread to other areas of the body and might cause symptoms there. Often, diagnosis is presumptive, and based on clinical findings and the identification of a malignant trophoblast.

You should be carefully monitored after a hydatidiform mole or at the end of a pregnancy.

Gestational choriocarcinoma

Most patients develop gestational choriocarcinoma shortly after gestational anomalies, but pathology may occur after a long latency of years. About Cancer generously supported by Dangoor Education since Irregular vaginal bleeding Pain, which may be associated with the bleeding, or due to enlargement of the ovaries that often occurs choriocarcinomx a choriocarcinoma. Stage 4 The abnormal cells have spread metastasised to other parts of the body, such as the liver or brain.

Ovarian serous cystadenoma Mucinous cystadenoma Cystadenocarcinoma Papillary serous cystadenocarcinoma Krukenberg tumor. Chemotherapy is the main type of treatment.

About persistent trophoblastic disease and choriocarcinoma | Choriocarcinoma | Cancer Research UK

A baby may or may not develop in this type of pregnancy. A choriocarcinoma is a cancer that happens when cells that were part of a normal pregnancy or a molar pregnancy become cancerous. Often, it happens after a growth of some sort in the womb pregnancy, tumor, mole, cyst [1].

Even a very small amount of molar tissue anywhere in the body can grow and cause problems.